Monterrey
3:1
Inter Miami CF 
Quarterfinals
Pachuca
2:1
Herediano 
Quarterfinals
Club America
5:2
New England Revolution 
Quarterfinals
Tigres
1:1
Columbus Crew 
Quarterfinals
Herediano
0:5
Pachuca
Quarterfinals
Inter Miami CF
1:2
Monterrey
Quarterfinals
New England Revolution
0:4
Club America
Quarterfinals
Columbus Crew
1:1
Tigres
Quarterfinals
Monterrey
2:1
FC Cincinnati 
Round of 16
Alajuelense
1:1
New England Revolution
Round of 16
Club America
2:3
Guadalajara 
Round of 16
Inter Miami CF
3:1
Nashville SC 
Round of 16
S.V. Robinhood
1:1
Herediano
Round of 16
Tigres
4:2
Orlando City 
Round of 16
Pachuca
6:0
Philadelphia Union 
Round of 16
Columbus Crew
1:1
Houston Dynamo 
Round of 16
Nashville SC
2:2
Inter Miami CF
Round of 16
FC Cincinnati
0:1
Monterrey
Round of 16
Guadalajara
0:3
Club America
Round of 16
Houston Dynamo
0:1
Columbus Crew
Round of 16
New England Revolution
4:0
Alajuelense
Round of 16
Orlando City
0:0
Tigres
Round of 16
Philadelphia Union
0:0
Pachuca
Round of 16
Herediano
2:0
S.V. Robinhood
Round of 16
New England Revolution
3:0
Independiente La Chorrera 
Round 1
Nashville SC
4:0
Moca FC 
Round 1
FC Cincinnati
4:0
Cavalier 
Round 1
Houston Dynamo
1:0
St. Louis City 
Round 1
Philadelphia Union
3:3
Saprissa 
Round 1
Orlando City
3:1
Cavalry FC 
Round 1
Cavalier
0:2
FC Cincinnati
Round 1
Moca FC
0:3
Nashville SC
Round 1
Cavalry FC
0:3
Orlando City
Round 1
Independiente La Chorrera
0:1
New England Revolution
Round 1
Saprissa
2:3
Philadelphia Union
Round 1
St. Louis City
2:1
Houston Dynamo
Round 1
Monterrey
3:0
Comunicaciones Guatemala 
Round 1
Toluca
2:3
Herediano
Round 1
Club America
2:0
Real Esteli 
Round 1
Tigres
3:0
Vancouver Whitecaps 
Round 1
Guadalajara
2:1
Forge FC 
Round 1
Vancouver Whitecaps
1:1
Tigres
Round 1
Forge FC
1:3
Guadalajara
Round 1
Herediano
1:2
Toluca
Round 1
Real Esteli
2:1
Club America
Round 1
Comunicaciones Guatemala
1:4
Monterrey
Round 1
